MICROWAVE-ASSISTED SUZUKI-MIYAURA CROSS COUPLING USING NICKEL AS CATALYST TO RAPIDLY ACCESS TO 3-ARYLAZETIDINE

Published in: Chemistry Select

By: Dr. Geoffroy Dequirez et al.

September 29, 2017

Link to the article


REVIVING A DRUG FOR TUBERCULOSIS ?

A compound called SMARt-420 renders ethionamide-resistant strains of Mycobacterium tuberculosis fully susceptible.

Published in: New England J. of Medicine, http://www.nejm.org/doi/full/10.1056/NEJMcibr1703502

June 8th, 2017

By: Eric J. Rubin


REVERSION OF ANTIBIOTIC RESISTANCE IN MYCOBACTERIUM TUBERCULOSIS BY SPIROISOXAZOLINE SMART-420

Published in: Science, March 17th, 2017, Vol. 355, Issue 6330, pp. 1206-1211

By: Nicolas Blondiaux et al.


A NOVEL GENOME-EDITING PLATFORM FOR DRUG-RESISTANT ACINETOBACTER BAUMANNII REVEALS AN ADER-UNRELATED TIGECYCLINE RESISTANCE MECHANISM

Published in: Antimicrob Agents Chemother 2016, 60:7263–7271. doi:10.1128/AAC.01275-16.

By: Trebosc V et al.


LIGAND EFFICIENCY DRIVEN DESIGN OF NEW INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS TRANSCRIPTIONAL REPRESSOR ETHR USING FRAGMENT GROWING, MERGING, AND LINKING APPROACH

Published in:J. Med. Chem. 2014,57(11),pp 4876–4888

By: Villemagne B et al.


BIOVERSYS WORKS TO BRING ANTIBIOTIC RESISTANCE TO AN END

Published in: CHIMIA International Journal for Chemistry, Volume 68, Number 12, December 2014, pp. 888-890(3)

By: Tigges, Marcel; Gitzinger, Marc


ADJUVANT STRATEGIES FOR POTENTIATION OF ANTIBIOTICS TO OVERCOME ANTIMICROBIAL RESISTANCE.

Published in: Curr Opin Pharmacol. 2012 Oct;12(5):551-5. doi: 10.1016/j.coph.2012.07.005. Epub 2012 Jul 25

By: Pieren M, Tigges M


PHENYLETHYL BUTYRATE ENHANCES THE POTENCY OF SECOND-LINE DRUGS AGAINST CLINICAL ISOLATES OF MYCOBACTERIUM TUBERCULOSIS.

Published in: Antimicrob Agents Chemother. 2012 Feb;56(2):1142-5. doi: 10.1128/AAC.05649-11. Epub 2011 Nov 21

By: Grau T et al.


DISCOVERY OF NOVEL N-PHENYLPHENOXYACETAMIDE DERIVATIVES AS ETHR INHIBITORS AND ETHIONAMIDE BOOSTERS BY COMBINING HIGH-THROUGHPUT SCREENING AND SYNTHESIS.

Published in: J. Med. Chem., 2012 vol. 55(14) pp. 6391-402

By: Flipo M et al.


TUBERCULOSIS: THE DRUG DEVELOPMENT PIPELINE AT A GLANCE.

Published in: Eur J Med Chem, 2012 vol. 51 pp. 1-16

By: Villemagne B et al.